Malware Bytes installed or recently updated or antivirus is running without Sage 300 CRE exclusions set.

• Malware Bytes: Contact your IT administrator to uninstall Malware Bytes or set exclusions for Sage 300 CRE and Actian/Pervasive software.
• Windows Security/Windows Defender: Contact your IT administrator to set exclusions for Sage 300 CRE and Actian/Pervasive software.
• Other Antivirus: Contact your IT administrator to set exclusions for Sage 300 CRE and Actian/Pervasive software.

Refer to What Sage 300 Construction and Real Estate and Sage Estimating files and folders should I exclude from my antivirus software scan?

For other possible causes and solutions:

• Error: "This program has quit. I/O error." (during PM trial run tasks - Cache engine turned off) 
• Error: "Error creating temporary file in \\[directory path]\tmp. Make sure this directory is accessible and try again, or check with your Network Administrator for further assistance." (during PM Trial run tasks)
• Error: "Aborted. I/O error" (during PM Trial Run tasks on a terminal server, RDS server, or remote connection)

[BCB:156:Chat 300 CRE US:ECB]

Error: "Aborted. I/O error" or "Failed" (during PM Trial Run tasks)
How is the Property Management Trial Run task different from the Create Entries task?
Error: "PMDataAccessLayer Error creating temporary file" (during PM Trial run tasks)